Bioactive Small Molecules
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Filtered Search Results
Cayman Chemical ANTIBODY 5R 6S-EET 50UG
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An oxylipin; depolarizes transepithelial voltage in isolated rabbit renal cortical collecting duct when applied to the luminal side at 1 µM but to a lesser extent than 5S(6R)-EET; degrades in solution into 5,6-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS
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Medchemexpress LLC FMOC-NIP-OH 1G
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5000208599 FMOC-NIP-OH 1G
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Medchemexpress LLC Ivacaftor | 873054-44-5 | 99.9% | 100 MG
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Ivacaftor is a potent and orally bioavailable compound that functions as a CFTR potentiator. It is effective in targeting both G551D-CFTR and F508del-CFTR mutations, demonstrating EC50s of 100 nM and 25 nM respectively. This product is intended for research use only.
- Potent CFTR potentiator
- Orally bioavailable
- Targets G551D-CFTR
- Targets F508del-CFTR
- For research use only
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Medchemexpress LLC COPPER II PERCHLORA 10G
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5000208375 COPPER II PERCHLORA 10G
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Medchemexpress LLC Tert-butyl (4-iodobutyl)carbamate | 262278-40-0 | MFCD09951820 | 98.0% | 299.15 g/mol | C9H18INO2 | 500 MG
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Tert-butyl (4-iodobutyl)carbamate is a Boc-protected 4-iodobutyl carbamate used as a four-carbon linker in organic synthesis. The Boc protecting group can be removed under mild acidic conditions to reveal a free amine, and the iodine provides a reactive leaving group for nucleophilic substitution and further functionalization.
- Four-carbon linker for introduction of Boc-protected aminoalkyl chains.
- Boc group removable under mild acidic conditions to yield free amine.
- Iodine atom enables nucleophilic substitution and cross-coupling reactions.
- Commonly supplied at high purity for synthetic applications.
- Available in multiple pack sizes to suit small-scale synthesis and scale-up.
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Medchemexpress LLC FLURALANER INTERMEDI 100G
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5000208210 FLURALANER INTERMEDI 100G
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Medchemexpress LLC NICKEL II FLUORIDE 50G
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5000208204 NICKEL II FLUORIDE 50G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000290259 TMED9 HUMAN HEK293 100UG
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Selleck Chemical LLC DT2216-1mg
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DT2216 is a potent and selective degrader of BCL-XL based on PROTAC technology. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets.
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Medchemexpress LLC AR420626 10mM 1mL | 1798310-55-0 | 417.29 | C21H18Cl2N2O3 | 1 ML
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AR420626 is a selective agonist of free fatty acid receptor 3 (FFAR3) supplied for research use. It is offered as a 10 mM solution in DMSO (1 mL) and is reported to have high purity, making it suitable for in vitro pharmacology and signaling pathway studies.
- Selective FFAR3 agonist with reported nanomolar activity
- Supplied as a 10 mM solution in DMSO (1 mL)
- High reported purity (approximately 98.3%)
- Suitable for in vitro pharmacology and signaling studies
- Available as solid for custom preparations
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Cayman Chemical 9 Z 11 E 13 Z-OctadecatrIe 5mg
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An ω-5 long-chain polyunsaturated fatty acid; has been found as a major component in pomegranate seed oil; binds to the AF2 domain of PPARγ (IC50 = 2.5 µM); increases PPARα and PPARγ activity in 3T3-L1 cells in a reporter assay
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BIOGEMS INTERNATIONAL INC IBMX 100mg
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IBMX is a general inhibitor of cyclic nucleotide phosphodiesterases, increasing the level of intracellular cAMP. It is used to increase cell differentiation, decrease proliferation, and induce apoptosis. IBMX is reported to inhibit TNF-alpha, reduce inflammation, and activate PKA.
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Selleck Chemical LLC HS-10296 hydrochloride E4886-1G
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HS-10296 hydrochloride(Almonertinib (hydrochloride) HS-10296 HCl) is an irreversible third-generation inhibitor of EGFR tyrosine kinase that demonstrates high selectivity for EGFR-sensitizing mutations T790M resistance mutation It exhibits inhibitory activity against T790M T790M/L858R and T790M/Del19 with IC50 of 0 37 nM 0 29 nM and 0 21 nM respectively It also exhibits anti-tumor activity
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Medchemexpress LLC Itopride hydrochloride | 122892-31-3 | 99.8% | 10 MM 1 ML
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Itopride hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. It enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, making it useful as a gastrointestinal prokinetic agent. It can be used for researching gastro-esophageal reflux disease (GERD).
- Potent dopamine-2 antagonist
- Acetylcholine esterase (AChE) inhibitor
- Enhances gastric motility through antidopaminergic and anti-acetylcholinesterasic actions
- Can be used as a gastrointestinal prokinetic agent
- Useful for researching gastro-esophageal reflux disease (GERD)
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Cayman Chemical ANTIBODY T-863 25mg
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A DGAT-1 inhibitor (IC50 = 15 nM); selective for DGAT-1 over DGAT-2 and ACAT-1 (IC50s = >10 and 12 μM, respectively); inhibits triacylglycerol synthesis in HuTu 80 cells (IC50 = 4 nM); reduces plasma triacylglycerol levels, the ratio of triacylglycerols:diacylglycerols, and body weight in a mouse model of diet-induced obesity at 20 mg/kg
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